Synthesis of the C1-C13 fragment of leucascandrolide A.
نویسندگان
چکیده
[reaction: see text] The synthesis of the C1-C13 fragment 3 of leucascandrolide A has been completed utilizing a stereoselective and regioselective reductive cleavage of a highly functionalized spiroketal to incorporate the cis-2,6-disubstituted tetrahydropyan. The spiroketal was constructed by addition of a lithiated pyrone 5 to aldehyde 6.
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ورودعنوان ژورنال:
- Organic letters
دوره 2 5 شماره
صفحات -
تاریخ انتشار 2000